ATG5 anticorps

N° du produit ABIN4901026

Cet anticorps Souris Monoclonal détecte spécifiquement ATG5 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATG5 anticorps (ABIN4901026)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ATG5 anticorps

Fonction: ATG5 is a protein encoded by the ATG5 gene which is approximately 32,4 kDa. ATG5 is localised to the cytoplasm. It is involved in the autophagy pathway, longevity regulating pathway, the innate immune system and pink/parkin mediated mitophagy. It functions as an E1-like activating enzyme, in combination with autophagy protein 12, in a ubiquitin-like conjugating system. It is involved in multiple cellular processes such as mitochondrial quality control after oxidative damage, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. ATG5 is expressed ubiquitously in human tissues and mutations in the ATG5 gene may result in Bardet-Biedl syndrome. STJ98903 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous ATG5 protein.

Specificité: The antibody detects endogenous ATG5 protein.

Attributs du produit: Mouse Monoclonal to ATG5.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant peptide derived from ATG5.

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:10000-20000

Commentaires:

Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5

Poids moléculaire: 55kDa

ID gène: 9474

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy