ATG7 anticorps
Aperçu rapide pour ATG7 anticorps (ABIN4901029)
Antigène
Voir toutes ATG7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- ATG7 is a protein encoded by the ATG7 gene which is approximately 77,9 kDa. ATG7 is localised to the cytoplasm. It is involved in the autophagy pathway, class I MHC mediated antigen processing and presentation, the HIV life cycle and oncogenic MAPK signalling. It is an E1-like activating enzyme that is essential for autophagy and transport from the cytoplasm to the vacuole. It is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. ATG7 is expressed in the nervous system, liver, kidney, intestine and lung. STJ98914 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous ATG7 protein.
-
Specificité
- The antibody detects endogenous ATG7 protein.
-
Attributs du produit
- Mouse Monoclonal to ATG7.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Recombinant peptide derived from ATG7.
-
-
-
-
Indications d'application
-
WB 1:500-2000
ELISA 1:10000-20000 -
Commentaires
-
Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
Autre désignation
- ATG7
-
Poids moléculaire
- 78kDa
-
ID gène
- 10533
-
UniProt
- O95352
-
Pathways
- Response to Water Deprivation, Autophagy
Antigène
-