PPARD anticorps

N° du produit ABIN4902153

Cet anticorps anti-PPARD est un anticorps Souris Monoclonal détectant PPARD dans IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PPARD anticorps (ABIN4902153)

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARD est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2F9

Détail du produit anti-PPARD anticorps

Fonction: PPAR delta is a protein encoded by the PPARD gene which is approximately 49,9 kDa. PPAR delta is localised to the nucleus. It is involved in pyruvate metabolism and the citric acid cycle, gene expression, metabolism and nuclear receptor transcription pathway. This protein falls under the peroxisome proliferator-activated receptor family. It is a nuclear hormone receptor that binds peroxisome proliferators and controls the size and number of peroxisomes produced by cells. It may also function as an integrator of transcription repression and nuclear receptor signalling. PPAR delta is ubiquitously expressed with the highest levels in the placenta and skeletal muscle. Mutations in the PPARD gene may result in atherosclerosis. STJ97707 was developed from clone 2F9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PPAR delta.

Specificité: PPAR Delta Mouse Monoclonal Antibody (2F9) detects endogenous levels of PPAR Delta

Attributs du produit: Mouse Monoclonal to PPAR Delta.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Recombinant peptide derived from PPAR Delta

Isotype: IgG1

Information d'application

Indications d'application: IHC 1:100-200

Commentaires:

Ubiquitous with maximal levels in placenta and skeletal muscle.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur PPARD

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Autre désignation: PPAR Delta

ID gène: 5467

UniProt: Q03181

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation