Ubiquitin anticorps

N° du produit ABIN4902435

Cet anticorps anti-Ubiquitin est un anticorps Souris Monoclonal détectant Ubiquitin dans WB et IHC (p). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour Ubiquitin anticorps (ABIN4902435)

Antigène: Ubiquitin (Ub)

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ubiquitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5F1

Détail du produit anti-Ubiquitin anticorps

Fonction: Ubiquitin is a protein encoded by the UBB gene which is approximately 25,7 kDa. Ubiquitin is localised to the cytoplasm and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, RET signalling, activated TLR4 signalling and signalling by Notch1. It is one of the most conserved proteins known and has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression and the stress response. Ubiquitin is expressed in the nervous system, blood, liver and pancreas. Mutations in the UBB gene may result in a cleft palate. STJ97742 was developed from clone 5F1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of ubiquitin.

Specificité: Ubiquitin Mouse Monoclonal Antibody (5F1) detects endogenous levels of Ubiquitin

Attributs du produit: Mouse Monoclonal to Ubiquitin.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: synthetic peptide derived from Ubiquitin

Isotype: IgG1

Information d'application

Indications d'application: WB 1:1000-2000
IHC 1:100-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur Ubiquitin

Antigène: Ubiquitin (Ub)

Autre désignation: Ubiquitin

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway