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Hemoglobin Subunit beta anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Hemoglobin Subunit beta dans WB, IHC et FACS. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN4903870

Aperçu rapide pour Hemoglobin Subunit beta anticorps (ABIN4903870)

Antigène

Voir toutes Hemoglobin Subunit beta (HBB) Anticorps
Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reactivité

  • 49
  • 13
  • 8
  • 8
  • 8
  • 2
  • 1
Humain, Souris, Rat

Hôte

  • 51
  • 20
Lapin

Clonalité

  • 54
  • 18
Polyclonal

Conjugué

  • 32
  • 11
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Hemoglobin Subunit beta est non-conjugé

Application

  • 59
  • 32
  • 15
  • 14
  • 14
  • 8
  • 5
  • 4
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Attributs du produit

    Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3, 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-1-3') and (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-2 cleavage plane. When the two å1-2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains.

    Purification

    Affinity purification

    Immunogène

    Recombinant protein of human HBB.

    Isotype

    IgG
  • Indications d'application

    WB 1:100-1:200 , IHC 1:50-1:100 , FC 1:20-1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C.
  • Antigène

    Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

    Autre désignation

    HBB

    ID gène

    3043

    UniProt

    P68871
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