ALAD anticorps (AA 151-240) (AbBy Fluor® 594)

N° du produit ABIN2809601

Cet anticorps anti-ALAD est un anticorps Lapin Polyclonal détectant ALAD dans WB, IF (cc) et IF (p). Adapté pour Souris.

Aperçu rapide pour ALAD anticorps (AA 151-240) (AbBy Fluor® 594) (ABIN2809601)

Antigène: ALAD (Aminolevulinate Dehydratase (ALAD))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAD est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ALAD anticorps (AbBy Fluor® 594)

Épitope: AA 151-240

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ALAD

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ALAD

Antigène: ALAD (Aminolevulinate Dehydratase (ALAD))

Autre désignation: ALAD

Sujet:

Synonyms: ALAD, ALADH, ALADR, Aminolevulinate dehydratase, Aminolevulinate, delta, dehydratase, Delta aminolevulinic acid dehydratase, Delta-aminolevulinic acid dehydratase, HEM2_HUMAN, Lv, PBGS, Porphobilinogen synthase.

Background: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP). AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.

ID gène: 210

UniProt: P13716