ALDH1A1 anticorps

N° du produit ABIN4906006

Détail du produit anti-ALDH1A1 anticorps

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ALDH1A1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This ALDH1A1 monoclonal antibody is generated from mouse immunized with ALDH1A1 recombinant protein.

Clone: 2C2

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ALDH1A1

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Autre désignation: ALDH1A1 (ALDH1A1 Produits)

Synonymes: anticorps ALDC, anticorps ALDH-E1, anticorps ALDH1, anticorps ALDH11, anticorps PUMB1, anticorps RALDH1, anticorps AL1A1, anticorps aldc, anticorps aldh-e1, anticorps aldh1, anticorps aldh11, anticorps pumb1, anticorps raldh1, anticorps GGADHR, anticorps ALDH1A1, anticorps ALDDH, anticorps Ahd2, anticorps Aldh1, anticorps Aldh2, anticorps Ahd-2, anticorps Aldh1a2, anticorps E1, anticorps Raldh1, anticorps Aldh1a1, anticorps ALHDII, anticorps RALDH 1, anticorps RalDH1, anticorps aldehyde dehydrogenase 1 family member A1, anticorps aldehyde dehydrogenase 1 family, member A1, anticorps aldehyde dehydrogenase 1 family member A1 L homeolog, anticorps aldehyde dehydrogenase family 1, subfamily A1, anticorps aldehyde dehydrogenase, anticorps retinal dehydrogenase 1, anticorps ALDH1A1, anticorps aldh1a1, anticorps Aldh1a1, anticorps aldh1a1.L, anticorps aldH1, anticorps LOC100732581, anticorps LOC101822890

Sujet:

Synonyms: ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1, ALDH-E1, HEL-S-53e, Retinal dehydrogenase 1, RALDH 1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, ALDH1A1.

Background: ALDH1A1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. ALDH1A1 is the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. ALDH1A1 can convert/oxidize retinaldehyde to retinoic acid. ALDH1A1 may have a broader specificity and oxidize other aldehydes in vivo.

ID gène: 216

UniProt: P00352

Pathways: Dopaminergic Neurogenesis