BMI1 anticorps

N° du produit ABIN4906627

Cet anticorps Souris Monoclonal détecte spécifiquement BMI1 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour BMI1 anticorps (ABIN4906627)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 2T6

Détail du produit anti-BMI1 anticorps

Réactivité croisée: Humain

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: Optional[synonyms]: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

ID gène: 100532731, 648

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy