MCM3 anticorps

N° du produit ABIN4911831

Cet anticorps anti-MCM3 Monoclonal Souris (Clone 3C3) (ABIN4911831) détecte spécifiquement MCM3 dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MCM3 anticorps (ABIN4911831)

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MCM3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 3C3

Détail du produit anti-MCM3 anticorps

Fonction: MCM3 (3C3) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein G.

Immunogène: This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3.

Isotype: IgG1

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MCM3

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Autre désignation: MCM3

Sujet:

Synonyms: HCC5, P1.h, RLFB, P1-MCM3, DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, RLF subunit beta, p102, MCM3

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

ID gène: 4172

UniProt: P25205

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA