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MGMT anticorps

MGMT Reactivité: Humain WB, IF, IHC (p) Hôte: Souris Monoclonal 4C12 unconjugated
N° du produit ABIN4911931
  • Antigène Voir toutes MGMT Anticorps
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Reactivité
    • 72
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 69
    • 10
    Souris
    Clonalité
    • 62
    • 17
    Monoclonal
    Conjugué
    • 44
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MGMT est non-conjugé
    Application
    • 54
    • 33
    • 21
    • 20
    • 13
    • 13
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
    Clone
    4C12
    Isotype
    IgG1
    Top Product
    Discover our top product MGMT Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF()
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Autre désignation
    MGMT (MGMT Produits)
    Synonymes
    anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt
    Sujet

    Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    ID gène
    4255
    UniProt
    P16455
    Pathways
    Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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