TBP anticorps

N° du produit ABIN4914538

Cet anticorps Souris Monoclonal détecte spécifiquement TBP dans WB, IHC (p) et IF (cc). Il présente une réactivité envers Humain, Souris, Rat et Cynomolgus.

Aperçu rapide pour TBP anticorps (ABIN4914538)

Antigène: TBP (TATA Box Binding Protein (TBP))

Reactivité: Humain, Souris, Rat, Cynomolgus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 8C4

Détail du produit anti-TBP anticorps

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Cynomolgus Monkey

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: Purified His-tagged TBP protein was used to produced this monoclonal antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TBP

Antigène: TBP (TATA Box Binding Protein (TBP))

Autre désignation: TBP

Sujet:

Synonyms: HDL4, GTF2D, SCA17, TFIID, GTF2D1, TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, TBP, TF2D

Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

ID gène: 6908

UniProt: P20226

Pathways: Signalisation WNT