USP14 anticorps

N° du produit ABIN4915065

Cet anticorps anti-USP14 est un anticorps Souris Monoclonal détectant USP14 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour USP14 anticorps (ABIN4915065)

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP14 est non-conjugé

Application: Western Blotting (WB)

Clone: 9C1

Détail du produit anti-USP14 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur USP14

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Autre désignation: USP14

Sujet:

Synonyms: TGT, Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14

Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

ID gène: 9097

UniProt: P54578