Dityrosine anticorps

N° du produit ABIN492669

Cet anticorps anti-Dityrosine est un anticorps Souris Monoclonal détectant Dityrosine dans WB, EIA et IHC (p). Adapté pour . Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Dityrosine anticorps (ABIN492669)

Antigène: Dityrosine (DT)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dityrosine est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1C3

Détail du produit anti-Dityrosine anticorps

Purification: Protein A Chromatography

Immunogène: 3-(p-hydroxyphenyl) propionic acid dimer KLH-conjugated

Isotype: IgG2a

Information d'application

Indications d'application: ELISA (Ref.1,2)Western bLot (Ref.3,5)Immunohistochemistry on Paraffin Sections (Ref.4).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in 200 μL aqua bidest to 0.1 mg/mL

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °CAfter reconstitution, store as frozen aliquotsAvoid repeated freezing and thawingShelf life: One year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-Dityrosine (ABIN492669)

Li, Shi, Ding, Ran, Le: "Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys." dans: Amino acids, Vol. 49, Issue 2, pp. 241-260, (2018) (PubMed).

Détails sur Dityrosine

Antigène: Dityrosine (DT)

Autre désignation: Dityrosine / DT

Classe de substances: Dipeptide

Sujet: Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.