Recombinant CD34 anticorps (full length)
Aperçu rapide pour Recombinant CD34 anticorps (full length) (ABIN4949293)
Antigène
Voir toutes CD34 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Recombinant CD34 Antibody / Rabbit Monoclonal (azide and preservative free)
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Purification
- Protein A affinity chromatography
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Immunogène
- Recombinant full-length human protein was used as the immunogen for the recombinant CD34 antibody.
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Isotype
- IgG, kappa
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Indications d'application
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Optimal dilution of the recombinant CD34 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant CD34 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD34
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Autre désignation
- CD34
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Sujet
- This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85 % of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
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UniProt
- P28906
Antigène
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