PTH anticorps (N-Term)

N° du produit ABIN4949381

Cet anticorps anti-PTH est un anticorps Lapin Polyclonal détectant PTH dans IF, FACS et IHC (p). Adapté pour Humain.

Aperçu rapide pour PTH anticorps (N-Term) (ABIN4949381)

Antigène: PTH (Parathyroid Hormone (PTH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTH est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PTH anticorps

Épitope: N-Term

Purification: Protein A affinity chromatography

Immunogène: A synthetic peptide from the N-terminal region of human Parathyroid hormone was used as the immunogen for the PTH antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PTH antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the PTH antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur PTH

Antigène: PTH (Parathyroid Hormone (PTH))

Autre désignation: Parathyroid Hormone

Classe de substances: Hormone

Sujet: PTH/Parathyroid hormone is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Pathways: cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process