SELPLG anticorps

N° du produit ABIN4949414

Cet anticorps anti-SELPLG est un anticorps Souris Monoclonal détectant SELPLG dans FACS, IF et IHC (p). Adapté pour Humain.

Aperçu rapide pour SELPLG anticorps (ABIN4949414)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PSGL1-1601

Détail du produit anti-SELPLG anticorps

Purification: Protein G affinity

Immunogène: Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the PSGL-1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the PSGL-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162 / P selectin glycoprotein ligand 1 / PSGL-1

Sujet: P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.