BAFF anticorps

N° du produit ABIN4949453

Cet anticorps anti-BAFF est un anticorps Souris Monoclonal détectant BAFF dans FACS et IF. Adapté pour Humain.

Aperçu rapide pour BAFF anticorps (ABIN4949453)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: C257-1638

Détail du produit anti-BAFF anticorps

Purification: Protein G affinity chromatography

Immunogène: Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.

Isotype: IgG1

Information d'application

Indications d'application: Titering of the BAFF antibody may be required for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in sterile PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: BAFF antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF / BLyS

Sujet: BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31  kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response