Calnexin anticorps

N° du produit ABIN4949485

L’anticorps Souris Monoclonal anti-Calnexin a été validé pour WB, ELISA, IHC (p) et IF/ICC. Il convient pour détecter Calnexin dans des échantillons de Humain.

Aperçu rapide pour Calnexin anticorps (ABIN4949485)

Antigène: Calnexin (CANX)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)

Clone: CANX-1541

Détail du produit anti-Calnexin anticorps

Aucune reactivité croisée: Rat (Rattus)

Purification: Protein G affinity chromatography

Immunogène: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Titering of the Calnexin antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL (order BSA-free format for coating),WB: 1-2 μg/mL,IF/ICC: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Calnexin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: Calnexin

Sujet: It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis