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Calnexin anticorps

CANX Reactivité: Humain WB, ELISA, IHC (p), IF/ICC Hôte: Souris Monoclonal CANX-1541 unconjugated
N° du produit ABIN4949485
  • Antigène Voir toutes Calnexin (CANX) Anticorps
    Calnexin (CANX)
    Reactivité
    • 116
    • 75
    • 74
    • 50
    • 34
    • 31
    • 31
    • 29
    • 29
    • 26
    • 25
    • 25
    • 22
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    • 20
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 116
    • 23
    • 7
    Souris
    Clonalité
    • 114
    • 33
    Monoclonal
    Conjugué
    • 70
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calnexin est non-conjugé
    Application
    • 122
    • 80
    • 55
    • 54
    • 41
    • 27
    • 26
    • 24
    • 20
    • 14
    • 13
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)
    Aucune reactivité croisée
    Rat (Rattus)
    Purification
    Protein G affinity chromatography
    Immunogène
    A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
    Clone
    CANX-1541
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CANX Anticorps primaire
  • Indications d'application
    Titering of the Calnexin antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL (order BSA-free format for coating),WB: 1-2 μg/mL,IF/ICC: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the Calnexin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    Calnexin (CANX)
    Autre désignation
    Calnexin (CANX Produits)
    Synonymes
    anticorps CNX, anticorps IP90, anticorps P90, anticorps 1110069N15Rik, anticorps AI988026, anticorps Cnx, anticorps D11Ertd153e, anticorps canx, anticorps clgn, anticorps clnx, anticorps cnx, anticorps PP90, anticorps zgc:63524, anticorps wu:fe06b12, anticorps CANX, anticorps calnexin, anticorps CalNeXin, anticorps calnexin L homeolog, anticorps CANX, anticorps Canx, anticorps cnx-1, anticorps canx.L, anticorps canx, anticorps LOC100283947
    Sujet
    It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
    Pathways
    Signalisation MAPK, Thyroid Hormone Synthesis
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