GJB1 anticorps (Cytoplasmic Loop)
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- Antigène Voir toutes GJB1 Anticorps
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Épitope
- Cytoplasmic Loop
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Reactivité
- Humain, Rat, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GJB1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purification
- Protein G affinity chromatography
- Immunogène
- Rat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1).
- Clone
- M12-13
- Isotype
- IgG
- Top Product
- Discover our top product GJB1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the Connexin 32 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL for 30 min at RT
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the Connexin 32 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
- Autre désignation
- Connexin 32 / GJB1 (GJB1 Produits)
- Synonymes
- anticorps GJIC, anticorps cmtx, anticorps cmtx1, anticorps connexin-30, anticorps connexin32, anticorps cx30, anticorps cx32, anticorps gja1, anticorps CX32, anticorps GJB1, anticorps AI118175, anticorps Cnx32, anticorps Cx32, anticorps Gjb-1, anticorps CMTX, anticorps CMTX1, anticorps gjb1-a, anticorps gap junction protein beta 1, anticorps connexin 32, anticorps probable serine/threonine-protein kinase CST, anticorps gap junction protein, beta 1, anticorps gap junction protein beta 1 L homeolog, anticorps gjb1, anticorps CX32, anticorps LOC9303136, anticorps GJB1, anticorps Gjb1, anticorps gjb1.L
- Sujet
- This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another.
- Pathways
- Cell-Cell Junction Organization
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