KRT15 anticorps (C-Term)

N° du produit ABIN4949584

L’anticorps anti-KRT15 Monoclonal Souris est utilisé pour la détection de KRT15 dans des échantillons de Humain et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour KRT15 anticorps (C-Term) (ABIN4949584)

Antigène: KRT15 (Keratin 15 (KRT15))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT15 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: LHK15

Détail du produit anti-KRT15 anticorps

Épitope: C-Term

Fonction: Keratin 15 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Keratin 15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Keratin 15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur KRT15

Antigène: KRT15 (Keratin 15 (KRT15))

Autre désignation: Keratin 15

Sujet: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

UniProt: P19012