Desmin anticorps

N° du produit ABIN4949599

L’anticorps anti-Desmin Monoclonal Souris est utilisé pour la détection de Desmin dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IF, IHC (p) et FACS.

Aperçu rapide pour Desmin anticorps (ABIN4949599)

Antigène: Desmin (DES)

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: DES-1711

Détail du produit anti-Desmin anticorps

Fonction: Desmin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Recombinant human Desmin was used as the immunogen for the Desmin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Desmin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Desmin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α,-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

UniProt: P17661