EPO anticorps

N° du produit ABIN4949655

Cet anticorps Souris Monoclonal détecte spécifiquement EPO dans WB, FACS, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour EPO anticorps (ABIN4949655)

Antigène: EPO (Erythropoietin (EPO))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPO est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EPO-1368

Détail du produit anti-EPO anticorps

Purification: Protein G affinity chromatography

Immunogène: A human partial recombinant protein was used as the immunogen for the EPO antibody.

Isotype: IgG

Information d'application

Indications d'application: Titering of the EPO antibody may be required for optimal performance.

1. Required HIER: boil tissue sections in 10  mM citrate buffer,  pH 6, for 10-20 min.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL,Immunohistochemistry (FFPE): 4-8 μg/mL for 30 min at RT (1),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the EPO antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur EPO

Antigène: EPO (Erythropoietin (EPO))

Autre désignation: Erythropoietin / EPO

Classe de substances: Hormone

Sujet: Erythropoietin / EPO is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.

Pathways: Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity