LHCGR anticorps (N-Term)

N° du produit ABIN4949739

Détail du produit anti-LHCGR anticorps

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Protein G affinity chromatography

Immunogène: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.

Clone: LHCGR-1415

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the hCG Receptor antibody should be determined by the researcher.\. FACS: 0.5-1 μg/million cells in 0.1ml,IF: 1-2 μg/mL,WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the hCG Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: hCG Receptor / LH Receptor (LHCGR Produits)

Synonymes: anticorps HHG, anticorps LCGR, anticorps LGR2, anticorps LH/CG-R, anticorps LH/CGR, anticorps LHR, anticorps LHRHR, anticorps LSH-R, anticorps ULG5, anticorps Gpcr19-rs1, anticorps LH-R, anticorps Lhr, anticorps LSHR, anticorps lhr, anticorps GTHR-II, anticorps zfGTHR-II, anticorps LHCGR, anticorps LOC100222883, anticorps lh-r, anticorps LOC100305044, anticorps luteinizing hormone/choriogonadotropin receptor, anticorps luteinizing hormone/choriogonadotropin receptor L homeolog, anticorps luteinizing hormone receptor, anticorps LHCGR, anticorps Lhcgr, anticorps lhcgr, anticorps lhcgr.L, anticorps lhr, anticorps LOC100305044

Sujet: Recognizes a protein of 78-85  kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling