LHCGR anticorps (N-Term)

N° du produit ABIN4949743

L’anticorps anti-LHCGR Monoclonal Souris est utilisé pour la détection de LHCGR dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour LHCGR anticorps (N-Term) (ABIN4949743)

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: LHCGR-1417

Détail du produit anti-LHCGR anticorps

Épitope: N-Term

Fonction: LHR Antibody / hCG Receptor (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the LHR antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the LHR antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the LHR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: LHR

Sujet: Recognizes a protein of 78-85 kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin (LHR/CGR). Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling