L’anticorps anti-Podoplanin Monoclonal produit chez le Souris a été validé pour WB, FACS, IF et IHC (p). Il convient pour la détection de Podoplanin dans des échantillons provenant de Humain.
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Optimal dilution of the Podoplanin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Antigène
Podoplanin (PDPN)
Autre désignation
Podoplanin / gp36
Sujet
Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.