Transferrin Receptor anticorps (Extracellular)

N° du produit ABIN4949928

Cet anticorps Souris Monoclonal détecte spécifiquement Transferrin Receptor dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Transferrin Receptor anticorps (Extracellular) (ABIN4949928)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TFRC-1817

Détail du produit anti-Transferrin Receptor anticorps

Épitope: AA 94-212, Extracellular

Fonction: CD71 Antibody / Transferrin Receptor (Extracellular domain) (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the CD71 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71

Sujet: It recognizes a ~85-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis