PLK1 anticorps (AA 86-430)
Aperçu rapide pour PLK1 anticorps (AA 86-430) (ABIN4952193)
Antigène
Voir toutes PLK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 86-430
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Purification
- Antigen affinity
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Immunogène
- Amino acids 86-430 of human PLK1 were used as the immunogen for the PLK1 antibody.
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Isotype
- IgG
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anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 Reactivité: Humain, Souris WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 3C11 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibodyPLK1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 4G11 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibodyPLK1 Reactivité: Humain WB, ELISA, IF, IP, PLA Hôte: Souris Monoclonal 2G12 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 Reactivité: Humain WB, IHC, IP, IHC (p), FACS Hôte: Souris Monoclonal 5C1 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 Reactivité: Humain, Chien WB, IHC, IP, IHC (p) Hôte: Souris Monoclonal 6C6 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 Reactivité: Humain WB, IHC, IP, IHC (p) Hôte: Souris Monoclonal 1D4 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 Reactivité: Humain, Chien, Singe WB, IF, IP, FACS Hôte: Souris Monoclonal 8C12 unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 201-300) antibodyPLK1 Reactivité: Humain WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibodyPLK1 Reactivité: Humain ELISA, ICC Hôte: Souris Monoclonal 1D1 unconjugated
anti-Polo-Like Kinase 1 (PLK1) antibodyPLK1 Reactivité: Humain WB, IHC, IP, IHC (p), FACS Hôte: Souris Monoclonal 3F12 unconjugated
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Indications d'application
- Optimal dilution of the PLK1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the PLK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Autre désignation
- PLK1
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Sujet
- Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.
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UniProt
- P53350
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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