IL1A anticorps (AA 177-206)
Aperçu rapide pour IL1A anticorps (AA 177-206) (ABIN3031433)
Antigène
Voir toutes IL1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 177-206
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 177-206 from human IL1A was used as the immunogen for this IL-1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the IL-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4°C for up to one month. For long term, aliquot the IL-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL1A (Interleukin 1 alpha (IL1A))
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Autre désignation
- IL1 alpha
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Sujet
- IL1A is produced by activated macrophages and stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [UniProt]
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UniProt
- P01583
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Pathways
- Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
Antigène
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