NLRP12 anticorps

N° du produit ABIN3032018

Détail du produit anti-NLRP12 anticorps

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogène: This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Clone: 228CT4-1-3

Isotype: IgM kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NALP12 (NLRP12) (NLRP12 Produits)

Synonymes: anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508

Sujet: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome