SIRT6 anticorps

N° du produit ABIN4953432

Cet anticorps Souris Monoclonal détecte spécifiquement SIRT6 dans WB, IP, ICC et IF. Il présente une réactivité envers Humain, Souris, Rat et Primate.

Aperçu rapide pour SIRT6 anticorps (ABIN4953432)

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Reactivité: Humain, Souris, Rat, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 6C9-D10-D3

Détail du produit anti-SIRT6 anticorps

Purification: Protein G affinity

Immunogène: A human recombinant protein was used as the immunogen for this SIRT6 antibody.

Isotype: IgG1

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable

Restrictions: For Research Use only

Stockage

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Stock: -20 °C

Stockage commentaire: Store the SIRT6 antibody at -20°C.

Détails sur SIRT6

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Autre désignation: SIRT6

Sujet: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]

UniProt: Q8N6T7