APP anticorps (AA 736-770)

N° du produit ABIN3029926

Cet anticorps Lapin Polyclonal détecte spécifiquement APP dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour APP anticorps (AA 736-770) (ABIN3029926)

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-APP anticorps

Épitope: AA 736-770

Réactivité croisée (Details): Expected species reactivity: Mouse, Pig, Primate, Rat

Purification: Purified

Immunogène: A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Amyloid beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur APP

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Autre désignation: Amyloid beta Precusor Protein (APP)

Sujet: APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ, is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ, can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour