ATG5 anticorps (AA 209-238)

N° du produit ABIN3030035

L’anticorps Lapin Polyclonal anti-ATG5 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter ATG5 dans des échantillons de Humain et Souris.

Aperçu rapide pour ATG5 anticorps (AA 209-238) (ABIN3030035)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-ATG5 anticorps

Épitope: AA 209-238

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 209-238 from the human protein was used as the immunogen for this anti-ATG5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the anti-ATG5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the anti-ATG5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy