NLRP12 anticorps

N° du produit ABIN3032016

Cet anticorps anti-NLRP12 Polyclonal Lapin (ABIN3032016) détecte spécifiquement NLRP12 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NLRP12 anticorps (ABIN3032016)

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NLRP12 anticorps

Fonction: Anti-NLRP12 Antibody

Purification: Antigen affinity

Immunogène: This anti-NLRP12 antibody was produced from rabbits immunized with human NLRP12 recombinant protein.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the anti-NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the anti-NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NLRP12

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome