APC anticorps (AA 1148-1176)
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- Antigène Voir toutes APC Anticorps
- APC (Adenomatous Polyposis Coli (APC))
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Épitope
- AA 1148-1176
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APC est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 1148-1176 from the human protein was used as the immunogen for this APC antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product APC Anticorps primaire
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- Indications d'application
- Titration of the APC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the APC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- APC (Adenomatous Polyposis Coli (APC))
- Autre désignation
- APC (APC Produits)
- Synonymes
- anticorps dp2, anticorps dp3, anticorps fap, anticorps fpc, anticorps xapc, anticorps dp2.5, anticorps AI047805, anticorps AU020952, anticorps AW124434, anticorps CC1, anticorps Min, anticorps mAPC, anticorps BTPS2, anticorps DP2, anticorps DP2.5, anticorps DP3, anticorps GS, anticorps PPP1R46, anticorps RATAPC, anticorps APC1, anticorps APC, WNT signaling pathway regulator, anticorps adenomatous polyposis coli, anticorps adenomatous polyposis coli protein, putative, anticorps adenomatosis polyposis coli, anticorps adenomatous polyposis coli L homeolog, anticorps APC, anticorps apc, anticorps Smp_139190, anticorps Apc, anticorps apc.L
- Sujet
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
- UniProt
- P25054
- Pathways
- Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization
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