ATG13 anticorps (AA 1-30)

N° du produit ABIN3030086

L’anticorps Lapin Polyclonal anti-ATG13 a été validé pour WB, ELISA et IHC. Il convient pour détecter ATG13 dans des échantillons de Humain.

Aperçu rapide pour ATG13 anticorps (AA 1-30) (ABIN3030086)

Antigène: ATG13 (Autophagy Related 13 (ATG13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ATG13 anticorps

Épitope: AA 1-30

Réactivité croisée (Details): Expected species reactivity: Bovine

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for this ATG13 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ATG13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ATG13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ATG13

Antigène: ATG13 (Autophagy Related 13 (ATG13))

Autre désignation: ATG13

Sujet: ATG13 is an autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. [UniProt]

UniProt: O75143

Pathways: Signalisation PI3K-Akt, Autophagy