BACE1 anticorps (AA 476-501)
Aperçu rapide pour BACE1 anticorps (AA 476-501) (ABIN3030158)
Antigène
Voir toutes BACE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 476-501
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Réactivité croisée (Details)
- Expected species reactivity: Rat, Bovine
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Purification
- Purified
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Immunogène
- A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the BACE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Autre désignation
- BACE
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Sujet
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
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UniProt
- P56817
Antigène
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