CCR3 anticorps (AA 291-318)

N° du produit ABIN3030491

Détail du produit anti-CCR3 anticorps

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Épitope: AA 291-318

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Réactivité croisée (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 291-318 from the human protein was used as the immunogen for this CCR3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CCR3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CCR3

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Autre désignation: CCR3 (CCR3 Produits)

Synonymes: anticorps CC-CKR-3, anticorps CD193, anticorps CKR3, anticorps CMKBR3, anticorps CC-CKR3, anticorps Cmkbr1l2, anticorps Cmkbr3, anticorps C-C motif chemokine receptor 3, anticorps chemokine (C-C motif) receptor 3, anticorps CCR3, anticorps Ccr3

Sujet: CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.

UniProt: P51677