BIRC3 anticorps (AA 101-131)

N° du produit ABIN3030108

Cet anticorps anti-BIRC3 Polyclonal Lapin (ABIN3030108) détecte spécifiquement BIRC3 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour BIRC3 anticorps (AA 101-131) (ABIN3030108)

Antigène: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BIRC3 anticorps

Épitope: AA 101-131

Fonction: cIAP2 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the cIAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur BIRC3

Antigène: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Autre désignation: cIAP2

Sujet: BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.

UniProt: Q13489

Pathways: Apoptose, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades