Claudin 2 anticorps (AA 135-164)
Aperçu rapide pour Claudin 2 anticorps (AA 135-164) (ABIN3030535)
Antigène
Voir toutes Claudin 2 (CLDN2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 135-164
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Bovine
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Claudin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Claudin 2 (CLDN2)
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Sujet
- Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]
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UniProt
- P57739
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Pathways
- Hepatitis C
Antigène
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