DKK1 anticorps

N° du produit ABIN3030725

L’anticorps Lapin Polyclonal anti-DKK1 a été validé pour WB et ELISA. Il convient pour détecter DKK1 dans des échantillons de Humain et Souris.

Aperçu rapide pour DKK1 anticorps (ABIN3030725)

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DKK1 anticorps

Purification: Antigen affinity purified

Immunogène: This DKK1 antibody was produced from a rabbit immunized with a recombinant protein of human DKK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DKK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DKK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: DKK1

Sujet: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt]

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation