MAP3K12 anticorps

N° du produit ABIN3031847

Détail du produit anti-MAP3K12 anticorps

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K12 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antigen affinity purified

Immunogène: This DLK antibody was produced from rabbits immunized with a recombinant protein of human DLK.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DLK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DLK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MAP3K12

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Autre désignation: DLK (MAP3K12 Produits)

Synonymes: anticorps DLK, anticorps MEKK12, anticorps MUK, anticorps ZPK, anticorps ZPKP1, anticorps PK, anticorps Zpk, anticorps zgc:77370, anticorps MGC151798, anticorps dlk, anticorps map3k12, anticorps map3k12a, anticorps mekk12, anticorps muk, anticorps zpk, anticorps zpkp1, anticorps DKFZp459K2433, anticorps map3k12-a, anticorps map3k12-b, anticorps map3k12b, anticorps mitogen-activated protein kinase kinase kinase 12, anticorps mitogen activated protein kinase kinase kinase 12, anticorps mitogen-activated protein kinase kinase kinase 12 S homeolog, anticorps mitogen-activated protein kinase kinase kinase 12 L homeolog, anticorps MAP3K12, anticorps Map3k12, anticorps map3k12, anticorps map3k12.S, anticorps map3k12.L

Sujet: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

UniProt: P80370

Pathways: Signalisation MAPK