Dnmt2 anticorps (AA 346-375)
Aperçu rapide pour Dnmt2 anticorps (AA 346-375) (ABIN3029268)
Antigène
Voir toutes Dnmt2 (TRDMT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 346-375
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Fonction
- Dnmt2 Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 346-375 from the human protein was used as the immunogen for this Dnmt2 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Dnmt2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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Autre désignation
- Dnmt2
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Sujet
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O14717
Antigène
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