DNMT3B anticorps (AA 389-417)

N° du produit ABIN3030752

L’anticorps anti-DNMT3B Polyclonal Lapin est utilisé pour la détection de DNMT3B dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour DNMT3B anticorps (AA 389-417) (ABIN3030752)

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-DNMT3B anticorps

Épitope: AA 389-417

Fonction: Dnmt3b Antibody

Purification: Purified

Immunogène: A portion of amino acids 389-417 from the human protein was used as the immunogen for this Dnmt3b antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Dnmt3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Dnmt3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DNMT3B

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Autre désignation: Dnmt3b

Sujet: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome.

UniProt: Q9UBC3