DNMT3B anticorps (AA 1-80)

N° du produit ABIN7203336

L’anticorps anti-DNMT3B Polyclonal Lapin est utilisé pour la détection de DNMT3B dans des échantillons de Humain et Poulet. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour DNMT3B anticorps (AA 1-80) (ABIN7203336)

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reactivité: Humain, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DNMT3B anticorps

Épitope: AA 1-80

Fonction: Rabbit Anti-Dnmt3b Polyclonal Antibody

Specificité: Dnmt3b Polyclonal Antibody detects endogenous levels of Dnmt3b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Dnmt3b at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DNMT3B

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Autre désignation: Dnmt3b

Sujet: DNMT3B, DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIBCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Poids moléculaire: 96kD

ID gène: 1789

UniProt: Q9UBC3