DR1 anticorps (AA 83-112)

N° du produit ABIN3029101

Cet anticorps Lapin Polyclonal détecte spécifiquement DR1 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DR1 anticorps (AA 83-112) (ABIN3029101)

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DR1 anticorps

Épitope: AA 83-112

Réactivité croisée (Details): Expected species reactivity: Rat, Chicken

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 83-112 from the human protein was used as the immunogen for this DR1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur DR1

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Autre désignation: DR1 (Down-Regulator of Transcription 1)

Sujet: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

UniProt: Q01658