DYRK1A anticorps (AA 107-136)

N° du produit ABIN3030777

Cet anticorps anti-DYRK1A est un anticorps Lapin Polyclonal détectant DYRK1A dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour DYRK1A anticorps (AA 107-136) (ABIN3030777)

Antigène: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYRK1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DYRK1A anticorps

Épitope: AA 107-136

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Xenopus

Purification: Purified

Immunogène: A portion of amino acids 107-136 from the human protein was used as the immunogen for this DYRK1A antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DYRK1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DYRK1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur DYRK1A

Antigène: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Autre désignation: DYRK1A

Sujet: DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.

UniProt: Q13627

Pathways: Mitotic G1-G1/S Phases