Endothelin 3 anticorps (AA 168-197)

N° du produit ABIN3030805

Cet anticorps Lapin Polyclonal détecte spécifiquement Endothelin 3 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Endothelin 3 anticorps (AA 168-197) (ABIN3030805)

Antigène: Endothelin 3 (EDN3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Endothelin 3 anticorps

Épitope: AA 168-197

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the EDN3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: EDN3

Sujet: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

UniProt: P14138

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones