EIF2A anticorps (AA 437-465)

N° du produit ABIN3030889

Détail du produit anti-EIF2A anticorps

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Épitope: AA 437-465

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 437-465 from the human protein was used as the immunogen for this EIF2A antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the EIF2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the EIF2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur EIF2A

Antigène: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Autre désignation: EIF2A (EIF2A Produits)

Sujet: EIF2A functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. [UniProt]

UniProt: Q9BY44

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly