EIF2A anticorps (AA 437-465)
Aperçu rapide pour EIF2A anticorps (AA 437-465) (ABIN3030889)
Antigène
Voir toutes EIF2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 437-465
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Fonction
- EIF2A Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 437-465 from the human protein was used as the immunogen for this EIF2A antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the EIF2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the EIF2A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
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Autre désignation
- EIF2A
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Sujet
- EIF2A functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. [UniProt]
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UniProt
- Q9BY44
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Pathways
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
Antigène
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