FKBP1A anticorps (AA 43-74)

N° du produit ABIN3030968

L’anticorps anti-FKBP1A Polyclonal Lapin est utilisé pour la détection de FKBP1A dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour FKBP1A anticorps (AA 43-74) (ABIN3030968)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-FKBP1A anticorps

Épitope: AA 43-74

Fonction: FKBP12 Antibody

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Bovine, Rabbit

Purification: Purified

Immunogène: A portion of amino acids 43-74 from the human protein was used as the immunogen for this FKBP12 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the FKBP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the FKBP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP12

Sujet: FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process